Faculty News Department of Chemistry · Page 13 Nate Wittenberg During the past year the Wittenberg Lab was awarded an NIH grant to study the heterogeneity of biological nanoparticles (vesicles, synaptosomes, etc) by integrating particle nanoarrays with microfluidic devices. Graduate students Ashley Baxter, Megan Blauch, and Jennie Cawley presented their research at the Annual Meeting of the Biophysical Society in San Diego. In December we hosted a visiting undergraduate researcher, Hailey Nguyen, from Knox College in Galesburg, IL. Nate traveled to Chicago in early March to present two talks at PittCon 2020. One talk was on the analysis of membrane-membrane adhesion mediated by glycolipid-glycoprotein interactions. The other talk covered our work on photosensitized lipid oxidation and how it can alter the physical properties of biological membranes, including how light can be used to trigger changes in membrane curvature. In the 2019-2020 academic year the Wittenberg Lab published the following papers: Pisapati, A. V., Wang, Y., Blauch, M. E., Wittenberg, N. J., Cheng, X., Zhang, X. F. "Characterizing Single-Molecule Conformational Changes Under Shear Flow with Fluorescence Microscopy" Journal of Visualized Experiments 2020, 155, e60784. Baxter, A.M.; Wittenberg, N.J. "Excitation of Fluorescent Lipid Probes Accelerates Supported Lipid Bilayer Formation via Photosensitized Lipid Oxidation" Langmuir 2019, 35, 11542-11549. Jordan, L.R.; Blauch, M.E.; Baxter, A.M.; Cawley, J.E. and Wittenberg, N.J. "Influence of Brain Gangliosides on the Formation and Properties of Supported Lipid Bilayers. Colloids and Surfaces B Biointerfaces, 2019, 183, 110442. Vala, M.; Ertsgaard, C.T.; Wittenberg, N.J.; Oh, S.H. "Plasmonic Sensing on Symmetric Nanohole Arrays Supporting High-Q Hybrid Modes and Reflection Geometry" ACS Sensors, 2019, 4, 3265-3274. Ryu, Y.S.; Yun, H.; Chung, T.; Suh, J.H.; Kim, S.; Lee, K.; Wittenberg, N.J.; Oh, S.H. and Lee, B; Lee. S.D. "Kinetics of Lipid Raft Formation at Lipid Monolayer-Bilayer Junction Probed by Surface Plasmon Resonance" Biosensors & Bioelectronics, 2019, 142, 111568. David Vicic Since the last newsletter, the Vicic lab welcomed Fatema Amin as a new graduate student in the group. The published scientific contributions from the group included: Budnikova, Y.; Lancaster, K. M.; Vicic, D. A."[(MeCN)Ni(CF3)3]1– and [Ni(CF3)4]2– : Foundations Towards the Development of Trifluoromethylationsat Unsupported Nickel" Inorg. Chem. 2020, 59, 9143-9151. Shreiber. S. T.; Kaplan, P. T.; Hughes, R. P.; Vasiliu, M.; Dixon, D. A.; Cramer, R. E.; Vicic, D. A. "Syntheses, Solution Behaviour, and Computational Bond Length Analyses of Trifluoromethyl and Perfluoroethyl Cuprate Salts" J. Fluorine Chem. 2020, 234, 109518. Hu, W.-Q.; Pan, S.; Xu, X.-H.; Vicic, D. A.; Qing, F.-L. "Nickel-Mediated Trifluoromethylation of Phenol Derivatives via C−O Bond Activation" Angew. Chem. Int. Ed. 2020, 59, 2-9. Shreiber, S. T.; Scudder, J. J.; Vicic, D. A. “[(MeCN)3Co(C2F5)3]: A Versatile Precursor to Cobalt(III) Perfluoroethyl Complexes” Organometallics 2019, 38, 3169-3173. Yang, Y.; Zhou, Q.; Cai, J.; Xue, T.; Liu, Y.; Jiang, Y.; Luo, G.; Chung, L. W.; Vicic, D. A. “Exploiting the Trifluoroethyl Group as a Precatalyst Ligand in Nickel-Catalyzed Suzuki-Type Alkylations” Chem. Sci. 2019, 10, 5275-5282. Shreiber, S. T.; DiMucci, I. M.; Khrizanforov, M. N.; Titus, C. J.; Nordlund, D.; Dudkina, Y.; Cramer, R. E.;
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